Publications

2024

109. Assembly of the Tricyclic Core of Alopecurone C by Asymmetric Donor/Donor Carbene C-H Insertion. Yuan-Shin Shiue, Matthew W. Dyer, Noah P. Burlow, Nutthakarn Soisaeng, Kellan N. Lamb, Cristian Soldi, James C. Fettinger, Dean J. Tantillo, and Jared T. Shaw. Organic Letters ASAP.

108. Desymmetrization of Cyclic Sulfonimidamides by Asymmetric Allylation David A. Gutierrez, Garrett Toth-Williams, Croix J. Laconsay, Michael Yasuda, James C. Fettinger, Michael J. Di Maso, Jared T. Shaw. Angew. Chem. Int. Ed. 2024, 63, e202407114Description unavailable

2023

107. Deconvoluting Nonlinear Catalyst–Substrate Effects in the Intramolecular Dirhodium-Catalyzed C–H Insertion of Donor/Donor Carbenes Using Data Science Tools Lucas W. Souza, Beck R. Miller, Ryan C. Cammarota, Anna Lo, Ixchel Lopez, Yuan-Shin Shiue, Benjamin D. Bergstrom, Sarah N. Dishman, James C. Fettinger, Matthew S. Sigman*, and Jared T. Shaw*. ACS Catalysis 2024, 14, 1, 104-115

106. Catalytic generation of ortho-quinone dimethides via donor/donor rhodium carbenes Mingchun Gao, Jose M. Ruiz, Emily Jimenez, Anna Lo, Croix J. Laconsay, James C. Fettinger, Dean J. Tantillo and Jared T. Shaw* . Chem. Sci., 2023, 14, 6443-6448Graphical abstract: Catalytic generation of ortho-quinone dimethides via donor/donor rhodium carbenes

2022

105. One-Pot Assembly and Synthetic Applications of Geminal Acyl/Alkoxy Tetrasubstituted Allenes Benjamin D. Bergstrom*, Garrett Toth-Williams*, Anna Lo, Jeffrey W. Toman, James C. Fettinger and  Jared T. Shaw* . J. Org. Chem. 2022, 87, 18, 12175–12181

104. Divergent Asymmetric Synthesis of Panowamycins, TM-135, and Veramycin F Using C–H Insertion with Donor/Donor Carbenes Benjamin D. Bergstrom, Amy T. Merrill, James C. Fettinger, Dean J. Tantillo and  Jared T. Shaw* . Angew. Chem. Int. Ed. 2022, 61, e202203072Description unavailable

103. Diastereoselective Addition of Prochiral Nucleophilic Alkenes to α-Chiral N-Sulfonyl Imines David A. Gutierrez, James C. Fettinger, K.N. Houk, Kaori Ando* and  Jared T. Shaw* . Org. Lett. 2022, 24, 1164-1168

102. Divergent Stereochemical Outcomes in the Insertion of Donor/Donor Carbenes into the C–H Bonds of Stereogenic Centers Sarah N. Dishman, Croix J. Laconsay, James C. Fettinger, Dean J. Tantillo, and  Jared T. Shaw. Chem. Sci. 2022, 13, 1030-1036Graphical abstract: Divergent stereochemical outcomes in the insertion of donor/donor carbenes into the C–H bonds of stereogenic centers

101. 1,3-Asymmetric Induction in Diastereoselective Allylations of Chiral N-Tosyl Imines Anna Lo, David A. Gutierrez, Garrett Toth-WIlliams, James C. Fettinger, and  Jared T. Shaw. J. Org. Chem. 2022, 87, 2773-2778

2021

100. Mechanistic Investigation of Castagnoli-Cushman Multicomponent Reactions Leading to a Three-Component Synthesis of Dihydroisoquinolones Sara Y. Howard, Michael J. Di Maso, Kristin Shimabukuro, Noah P. Burlow, Darlene Q. Tan, James C. Fettinger, Thomas C. Malig, Jason E. Hein, and  Jared T. Shaw. J. Org. Chem. 2021, 86, 11599-11607

99. Highly Sensitive and Selective Spiropyran-Based Sensor for Copper(II) Quantification Kimberly M. Trevino, Brandon K. Tautges, Rohan Kapre, Francisco C. Franco Jr, Victor W. Or, Edward I. Balmond, Jared T. Shaw, Joel Garcia*, and Angelique Y. Louie*. ACS Omega. 2021, 6, 10776-10789

2020

98. Transition Metal Catalyzed Insertion Reactions with Donor/Donor Carbenes Jared T. Shaw*, Benjamin D. Bergstrom, Leslie A. Nickerson, Lucas W. Souza. Angew. Chem Int. Ed. 2020, 59, 2-17

97. Enantioselective Si–H Insertion Reactions of Diarylcarbenes for the Synthesis of Silicon-Stereogenic Silanes Jake R. Jagannathan, James C. Fettinger, Jared T. Shaw, and Annaliese K. Franz. J. Am. Chem. Soc. 2020, 142, 11675-11679

96. Synthesis and Comparative Evaluation of Photoswitchable Magnetic Resonance Imaging Contrast Agents Mingchun Gao, Bowen Shen, Junhan Zhou, Rohan Kapre, Angelique Y. Louie*, and Jared T. Shaw*. ACS Omega. 2020, 5, 14759-14666

95. Effect of Structure and Intramolecular Distances on Photoswitchable Magnetic Resonance Imaging Contrast Agents Bowen Shen, Mingchun Gao, Francisco C. Franco Jr., Rohan Kapre, Junhan Zhou, Xinzhe Li, Joel Garcia*, Jared T. Shaw*, and Angelique Y. Louie*. J. Org. Chem. 2020, 85, 7333-7341

94. C–H Insertion Reactions of Donor/Donor Carbenes: Inception, Investigation, and Insights Jared T. Shaw. Synlett. 2020, 31, 838-844

 

2019

93. Enantioselective Synthesis of Isochromans and Tetrahydroisoquinolines by C–H Insertion of Donor/Donor Carbenes Leslie A. Nickerson, Benjamin D. Bergstrom, Mingchun Gao, Yuan-Shin Shiue, Croix J. Laconsay, Matthew R. Culberson, Walker A. Knauss, James C. Fettinger, Dean J. Tantillo and Jared T. Shaw* Chem. Sci. 2020, 11, 494-498

92. Trapping and Electron Paramagnetic Resonance Characterization of the 5′dAdo• Radical in a Radical S-Adenosyl Methionine Enzyme Reaction with a Non-Native Substrate. Richard I. Sayler, Troy A. Stich, Sumedh Joshi, Nicole Cooper, Jared T. Shaw, Tadhg P. Begley, Dean J. Tantillo and David R. Britt*. ACS Cent. Sci. 2019, 5, 11, 1777-1785

91. Synthesis of Spirobicyclic Pyrazoles by Intramolecular Dipolar Cycloadditions/[1s, 5s] Sigmatropic Rearrangements. Christine A. Dimirjian, Marta Castiñeira Reis, Edward I. Balmond, Nolan C. Turman, Elys P. Rodriguez, Michael J. Di Maso, James C. Fettinger, Dean J. Tantillo, and Jared T. Shaw. Org. Lett. 2019, 21, 18, 7209-7212

90. Antioxidant Sensing by Spiropyrans: Substituent Effects and NMR Spectroscopic Studies. Joel Garcia, J. Bennett Addison, Stephen Z. Liu, Samuel Lu, Andrea L. Faulkner, Blanka M. Hodur, Edward I. Balmond, Victor W. Or, Jason H. Yun, Kimberly Trevino, Bowen Shen, Jared T. Shaw, Natia L. Frank, and Angelique Y. Louie.  J. Phys. Chem. B. 2019, 123 (31), 6799-6809.

89. Acyclic Stereocontrol in the Additions of Nucleophilic Alkenes to α‐Chiral N‐Sulfonyl Imines. Lucas C. Moore, Anna Lo, Jason S. Fell, Matthew R. Duong, Jose A. Moreno, Barry E. Rich, Martin Bravo, Dr. James C. Fettinger, Lucas W. Souza, Prof. Marilyn M. Olmstead, Kendall N. Houk*, and Jared T. Shaw*. Chem Eur. J. 2019, 25, 12214–12220

88. FtsZ-independent Mechanism of Division Inhibition by the Small Molecule PC190723 in Escherichia coli. Somya Khare, Jen Hsin, Nohemy A. Sorto, Gabriella M. Nepomuceno, Jared T. Shaw, Handuo Shi, and Kerwyn Casey Huang. Adv. Biosyst. 2019, 190021 (1-9).

87. Organocatalytic Mukaiyama Mannich Reactions of 2,5-Bis(trimethylsilyloxy)furan. Stephen W. Laws, Sara Y. Howard, Raquel Mato, Shuyu Meng, James C. Fettinger, and Jared T. Shaw. Org. Lett. 2019, 21, 13, 5073–5077

86. Formal [4 + 2] Cycloadditions of Anhydrides and α,β-Unsaturated N-Tosyl Ketimines. Noah P. Burlow, Sara Y. Howard, Carla M. Saunders , James C. Fettinger , Dean J. Tantillo , and Jared T. Shaw. Org. Lett. 2019, 21, 4, 1046-1049

 

2018

85. Canvass: A Crowd-sourced, Natural Product Screening Library for Exploring Biological Space. Sara E. Kearney, Gergely Zahoránszky-Kőhalmi, Kyle R. Brimacombe, Mark J. Henderson, Caitlin Lynch, Tongan Zhao, Kanny K. Wan, Zina Itkin, Christopher Dillon, Min Shen, Dorian M. Cheff, Tobie D. Lee, Danielle Bougie, Ken Cheng, Nathan P. Coussens, Dorjbal Dorjsuren, Richard T. Eastman, Ruili Huang, Michael J. Iannotti, Surendra Karavadhi, Carleen Klumpp-Thomas, Jacob S. Roth, Srilatha Sakamuru, Wei Sun, Steven A. Titus, Adam Yasgar, Ya-Qin Zhang, Jinghua Zhao, Rodrigo B. Andrade, M. Kevin Brown, Noah Z. Burns, Jin K. Cha, Emily E. Mevers, Jon Clardy, Jason A. Clement, Peter A. Crooks, Gregory D. Cuny, Jake Ganor, Jesus Moreno, Lucas A. Morrill, Elias Picazo, Robert B. Susick, Neil K. Garg, Brian C. Goess, Robert B. Grossman, Chambers C. Hughes, Jeffrey N. Johnston, Madeleine M. Joullie, A. Douglas Kinghorn, David G.I. Kingston, Michael J. Krische, Ohyun Kwon, Thomas J. Maimone, Susruta Majumdar, Katherine N. Maloney, Enas Mohamed, Brian T. Murphy, Pavel Nagorny, David E. Olson, Larry E. Overman, Lauren E. Brown, John K. Snyder, John A. Porco Jr., Fatima Rivas, Samir A. Ross, Richmond Sarpong, Indrajeet Sharma, Jared T. Shaw, Zhengren Xu, Ben Shen, Wei Shi, Corey R.J. Stephenson, Alyssa L. Verano, Derek S. Tan, Yi Tang, Richard E. Taylor, Regan J. Thomson, David A. Vosburg, Jimmy Wu, William M. Wuest, Armen Zakarian, Yufeng Zhang, Tianjing Ren, Zhong Zuo, James Inglese, Sam Michael, Anton Simeonov, Wei Zheng, Paul Shinn, Ajit Jadhav, Matthew B. Boxer, Matthew D. Hall*, Menghang Xia, Rajarshi Guha, and Jason M. Rohde. ACS Cent. Sci. 2018, 4 (12), 1727-1741.

84. Enantioselective Synthesis of Indolines, Benzodihydrothiophenes, and Indanes by C−H Insertion of Donor/Donor Carbenes. Lucas W. Souza*, Richard A. Squitieri*, Christine A. Dimirjian, Blanka M. Hodur, Leslie A. Nickerson, Corinne N. Penrod, Jesus Cordova, James C. Fettinger, and Jared T. Shaw. Angew. Chem. Int. Ed. 2018, 57, 15213–15216

 

2017

83. Synthesis of Benzodihydrofurans by Asymmetric C−H Insertion Reactions of Donor/Donor Rhodium Carbenes. Kellan N. Lamb, Richard A. Squitieri, Srinivasa R. Chintala, Ada J. Kwong, Edward I. Balmond, Cristian Soldi, Olga Dmitrenko, Marta Castiñeira Reis, Ryan Chung, J. Bennett Addison, James C. Fettinger, Jason E. Hein, Dean J. Tantillo, Joseph M. Fox, and Jared T. Shaw. Chem Eur J. 2017, 23, 11843–11855

82. Diastereoselective Base-Catalyzed Formal [4+2] Cycloadditions of N-Sulfonyl Imines and Cyclic Anhydrides. Stephen W. Laws, Lucas C. Moore, Michael J. Di Maso, Q. Nhu N. Nguyen, Dean J. Tantillo, and Jared T. Shaw. Org Lett. 2017, 19, 2466–2469

81. Targeting quinolone- and aminocoumarin-resistant bacteria with new gyramide analogs that inhibit DNA gyrase. K. Hurley, T. Santos, M. Fensterwald, M. Rajendran, J. Moore, E. Balmond, B. Blahnik, K. Faulkner, M. Foss, V. Heinrich, M. Lammers, L. Moore, G. Reynolds, G. Shearn-Nance, B. Stearns, Z. Yao, J. T. Shaw and D. Weibel. Med. Chem. Commun., 2017, 8, 942–951

 

2016

80. Asymmetric Synthesis of Homocitric Acid Lactone. Leslie A. Nickerson, Valerie Huynh, Edward I. Balmond, Stephen P. Cramer, and Jared T. Shaw. J. Org. Chem. 2016, 81, 11404-11408.

79. Comparative Evaluation of Substituent Effect on the Photochromic Properties of Spiropyrans and Spirooxazines. Edward I. Balmond, Brandon K. Tautges, Andrea L. Faulkner, Victor W. Or, Blanka M. Hodur, Jared T. Shaw, and Angelique Y. Louie. J. Org. Chem. 2016, 81, 8744–8758.

78. The Plastidial Metabolite MEcPP Induces a Transcriptionally Centered Stress-Response Hub via the Transcription Factor CAMTA3. Geoffrey Benn, Marta Bjornson, Haiyan Ke, Amancio De Souza, Edward I. Balmond, Jared T. Shaw, and Katayoon Dehesha. PNAS 2016, 113, 8855-8860.

77. Synthesis of Esters by in Situ Formation and Trapping of Diazoalkanes. Richard A. Squitieri, Galen P. Shearn-Nance, Jason E. Hein, and Jared T. Shaw. J. Org. Chem., 2016, 81, 5278–5284.

76. Synthesis of (±)-Bisavenanthramide B-6 by an Anionic Anhydride Mannich Reaction. Michael J. Di Maso, Gabriella M. Nepomuceno, Michael A. St. Peter, Haley H. Gitre, Kevin S. Martin, and Jared T. Shaw. Org. Lett. 2016, 18, 1740-1743.

75. Diastereoselective Synthesis of and Mechanistic Understanding for the Formation of 2-Piperidinones from Imines and Cyano-Substituted Anhydrides. Michael J. Di Maso, Kevin M. Snyder, Fábio De Souza Fernandes, Ommidala Pattawong, Darlene Q. Tan, James C. Fettinger, Paul Ha-Yeon Cheong, Jared T. Shaw. Chem. Eur. J. 2016, 22, 4794-4801.

74. Toward Structural Correctness: Aquatolide and the Importance of 1D Proton NMR FID Archiving. Guido F. Pauli, Matthias Niemitz, Jonathan Bisson, Michael W. Lodewyk, Cristian Soldi, Jared T. Shaw, Dean J. Tantillo, Jordy M. Saya, Klaas Vos, Roel A. Kleinnijenhuis, Henk Hiemstra, Shao-Nong Chen, James B. McAlpine, David C. Lankin, and J. Brent Friesen. J. Org. Chem. 2016, 81, 878-889.

73. Targeting the Bacterial Division Protein FtsZ. Katherine A. Hurley, Thiago M. A. Santos, Gabriella M. Nepomuceno, Valerie Huynh, Jared T. Shaw, and Douglas B. Weibel. J. Med. Chem., 2016, 59, 6975–6998.

 

2015

72. Preparation of a conjugation-ready thiol responsive molecular switch. Brandon Tautges, Victor Or, Joel Garcia, Jared T. Shaw, and Angelique Y. Louie. Tetrahedron Lett., 2015, 56, 6569-6573.

71. 4-Methyl-1-(2-(phenylsulfonyl)ethyl)-2,6,7-trioxabicyclo[2.2.2]octane. Michael J. Di Maso, Michael A. St. Peter, Jared T. Shaw . Org. Synth. 2015, 92, 328-341.

70. Synthesis of the Diaryl Ether Cores Common to Chrysophaentins A, E and F. Anthony J. Brockway, Charles I. Grove, Maximillian E. Mahoney, and Jared T. Shaw. Tetrahedron Lett., 2015, 2015, 56, 3396-3401.

69. Synthesis and Evaluation of Quinazolines as Inhibitors of the Bacterial Cell Division Protein FtsZ. Gabriella M. Nepomuceno, Katie M. Chan, Valerie Huynh, Kevin S. Martin, Jared T. Moore, Terrence E. O’Brien, Luiz A. E. Pollo, Francisco J. Sarabia, Clarissa Tadeus, Zi Yao, David E. Anderson, James B. Ames, and Jared T. Shaw. ACS. Med. Chem. Lett, 2015, 6(3), pp 308-312.

 

2014

68. Enantioselective Intramolecular C–H Insertion Reactions of Donor–Donor Metal Carbenoids. Cristian Soldi , Kellan N. Lamb , Richard A. Squitieri , Marcos González-López , Michael J. Di Maso , and Jared T. Shaw. J. Am. Chem. Soc., 2014, 136 (43), pp 15142–15145.

67. Failsafe Mechanisms Couple Division and DNA Replication in Bacteria.  Heidi A. Arjes, Allison Kriel, Nohemy A. Sorto, Jared T. Shaw, Jue D. Wang, and Petra Anne Levin.  Curr. Biol., 2014, 24 (18), 2149-2155.

66. Anhydride-Based Multicomponent Reactions.  Kevin S. Martin, Ashkaan Younai, and Jared T. Shaw. Multicomponent Reactions in Organic Synthesis (Wiley-Interscience; Ed. J. Zhu) 2014, 379-400.

65. Chapter 10 - Studies in the Synthesis of Biaryl Natural Products: The 6,6′-Binaphthopyranones. Michael J. Di Maso, Charles I. Grove, and Jared T. Shaw. Strategies and Tactics in Organic Synthesis, 2014, 10, pp 225-248.

64. Gyramides Prevent Bacterial Growth by Inhibiting DNA Gyrase and Altering Chromosome Topology. Manohary Rajendram, Katherine A. Hurley, Marie H. Foss, Kelsey M. Thornton, Jared T. Moore, Jared T. Shaw, and Douglas B. Weibel. ACS Chem. Biol. 2014, 9, 6, 1312-1319.

63. Diastereoselective Synthesis of gamma- and delta-Lactams From Imines and Sulfone-Substituted Anhydrides. Nohemy A. Sorto , Michael J. Di Maso, Manuel A. Muñoz , Ryan J. Dougherty , James C. Fettinger , and Jared T. Shaw. J. Org. Chem., 2014, 79 (6), pp 2601–2610.

 

2013

62. Nobody Can See Atoms: Science Camps Highlighting Approaches for Making Chemistry Accessible to Blind and Visually-Impaired Students. Henry B. Wedler, Lee Boyes, Rebecca L. Davis, Dan Flynn, Annaliese Franz, Christian S. Hamann, Jason G. Harrison, Michael W. Lodewyk, Kristin A. Milinkevich, Jared T. Shaw, Dean J. Tantillo, and Selina C. Wang.  J. Chem. Edu. 2014, 91 (2), 188-194.

61. Enantioselective Synthesis of Isotopically Labeled Homocitric Acid Lactone. Jared T. Moore, Nadine V. Hanhan, Maximillian E. Mahoney, Stephen P. Cramer, and Jared T. Shaw. Org. Lett., 2013, 15 (22), pp 5615–5617.

60. Stereoselective Synthesis of γ-Lactams from Imines and Cyanosuccinic Anhydrides. Darlene Q. Tan, Ashkaan Younai, Ommidala Pattawong, James C. Fettinger, Paul Ha-Yeon Cheong, and Jared T. Shaw. Org. Lett., Article, 15 (19), pp 5126–5129.

59. Stereocontrol in Asymmetric γ-Lactam Syntheses from Imines and Cyanosuccinic Anhydrides. Ommidala Pattawong, Darlene Q. Tan, James C. Fettinger, Jared T. Shaw, and Paul Ha-Yeon Cheong. Org. Lett., Article, 15 (19), pp 5130–5133.

58. Synthesis of a Library of "Lead-like" γ-Lactams by a One Pot, Four-Component Reaction. Kevin S. Martin, Michael J. Di Maso, James C. Fettinger, and Jared T. Shaw. ACS Comb. Sci., 2013, 15 (7), pp 356–362.

57. Design and Synthesis of Mimics of the T7-loop of FtsZ. Nohemy A. Sorto, Phillip P. Painter, James C. Fettinger, Dean J. Tantillo, and Jared T. Shaw. Org. Lett., 2013, 15 (11), pp 2700–2703.

56. Mechanism of Alkoxy Groups Substitution by Grignard Reagents on Aromatic Rings and Experimental Verification of Theoretical Predictions of Anomalous Reactions. Gonzalo Jimenez-Oses, Anthony J. Brockway, Jared T. Shaw, and K.N. Houk. J. Am. Chem. Soc., 2013, 135 (17), pp 6633–6642.

55. From Bead to Flask: Synthesis of a Complex β-Amino Amide for Probe Development Studies. Kevin S. Martin, Cristian Soldi, Kellan N. Candee, Hiromi I. Wettersten, Robert H. Weiss, and Jared T. Shaw. Beilstein J. Org. Chem. 2013, 9, 260-264.

 

2012

54. The Correct Structure of Aquatolide—Experimental Validation of a Theoretically-Predicted Structural Revision. Michael W. Lodewyk, Cristian Soldi, Paul B. Jones, Marilyn M. Olmstead, Juan Rita, Jared T. Shaw, and Dean J. Tantillo. J. Am. Chem. Soc., 2012, 134 (45), pp 18550–18553.

53. Catalytic Alkene Cyclization Reactions for the Stereoselective Synthesis of Complex “Terpenoid-like” Heterocycles. Jared T. Moore, Cristian Soldi, James C. Fettinger and Jared T. Shaw. Chem. Sci., 2013, 4, 292-296.

52. Comparison of Small Molecule Inhibitors of the Bacterial Cell Division Protein FtsZ and Identification of a Reliable Cross-Species Inhibitor. David E. Anderson, Michelle B. Kim, Jared T. Moore, Terrence E. O’Brien, Nohemy A. Sorto, Charles I. Grove, Laura L. Lackner, James B. Ames, and Jared T. Shaw. ACS Chem. Biol., 2012, 7 (11), pp 1918–1928.

51. Applied Computational Chemistry for the Blind and Visually Impaired. Henry B. Wedler, Sarah R. Cohen, Rebecca L. Davis, Jason G. Harrison, Matthew R. Siebert, Dan Willenbring, Christian S. Hamann, Jared T. Shaw, and Dean J. Tantillo. J. Chem. Educ. 2012, 89 (11), 1400-1404.

50. The Synthesis and Antimicrobial Activity of Heterocyclic Derivatives of Totarol. Michelle B. Kim, Terrence E. O'Brien, Jared T. Moore, David E. Anderson, Marie H. Foss, Douglas B. Weibel, James B. Ames, and Jared T. Shaw. ACS Med. Chem. Lett., 2012, 3, 818−822.

49. Strategic Applications of Multicomponent Reactions in Diversity-Oriented Synthesis. John M. Knapp, Mark J. Kurth, Jared T. Shaw, Ashkaan Younai. Diversity-Oriented Synthesis: Basics and Applications in Organic Synthesis, Drug Discovery, and Chemical Biology (Wiley-Interscience; Ed. A. Trabocchi), 2012, 29-57. 

48. Synthesis of 6,6′-Binaphthopyran-2-one Natural Products: Pigmentosin A, Talaroderxines A and B. Charles I. Grove, Michael J. Di Maso, Firoz A. Jaipuri, Michelle B. Kim, and Jared T. Shaw. Org. Lett., 2012, 14 (17), pp 4338–4341.

47. Inhibitors of Bacterial Tubulin Target Bacterial Membranes In Vivo. Marie H. Foss, Ye-Jin Eun, Charles I. Grove, Daniel A. Pauw, Nohemy A. Sorto, Jarred W. Rensvold, David J. Pagliarini, Jared T. Shaw, and Douglas B. Weibel. Med. Chem. Commun., 2013, 4, 112-119.

46. Characterization of Caulobacter Crescentus FtsZ Using Dynamic Light Scattering. Sen Hou, Stefan A. Wieczorek, Tomasz S. Kaminski, Natalia Ziebacz, Marcin Tabaka, Nohemy A. Sorto, Marie H. Foss, Jared T. Shaw, Martin Thanbichler, Douglas B. Weibel, Krzysztof Nieznanski, Robert Holyst, and Piotr Garstecki. J. Biol. Chem., 2012, 278, 23878-23886.

45. Influence of Chiral Thiols on the Diastereoselective Synthesis of γ-Lactams from Cyclic Anhydrides. Ashkaan Younai, James C. Fettinger, and Jared T. Shaw. Tetrahedron, 2012, 68 (22), pp 4320-4327.

44. Synthesis of a γ-Lactam Library via Formal Cycloaddition of Imines and Substituted Succinic Anhydrides. Darlene Q. Tan, Amy L. Atherton, Austin J. Smith, Cristian Soldi, Katherine A. Hurley, James C. Fettinger, and Jared T. Shaw. ACS Comb. Sci., 2012, 14 (3), pp 218–223.

43. Second-Generation Synthesis of (-)-Viriditoxin. Charles I. Grove, James C. Fettinger, and Jared T. Shaw. Synthesis, 2012, 44 (3), pp 362-371.

42. Carbon–Carbon Bond-Forming Reactions of α-Thioaryl Carbonyl Compounds for the Synthesis of Complex Heterocyclic Molecules. James E. Biggs-Houck, Rebecca L. Davis, Jingqiang Wei, Brandon Q. Mercado, Marilyn M. Olmstead, Dean J. Tantillo, and Jared T. Shaw. J. Org. Chem., 2012, 77 (1), pp 160–172.

 

2011

41. Direct Displacement of Alkoxy Groups of Vinylogous Esters by Grignard Reagents. Anthony Brockway, Marcos Gonzalez-Lopez, James C. Fettinger, and Jared T. Shaw. J. Org. Chem., 2011, 76 (9), pp 3515–3518.

40. Synthesis of (-)-Viriditoxin: A 6,6’-Binaphthopyran-2-one that Targets the Bacterial Cell Division Protein FtsZ. Young Sam Park, Charles I. Grove, Marcos Gonzalez-Lopez, Sameer Urgaonkar, James C. Fettinger, and Jared T. Shaw. Angew. Chem. Int. Ed., 2011, 50 (16), pp 3730–3733.

39. N-Benzyl-3-sulfonamidopyrrolidines Are a New Class of Bacterial DNA Gyrase Inhibitors. Marie H. Foss, Katherine A. Hurley, Nohemy A. Sorto, Laura L. Lackner, Kelsey M. Thornton, Jared T. Shaw, and Douglas B. Weibel. ACS Med. Chem. Lett., 2011, 2 (4), pp 289–292.

38. Ammonia synthons for the multicomponent assembly of complex γ-lactams. Darlene Q. Tan, Kevin S. Martin, James C. Fettinger, and Jared T. Shaw. PNAS, 2011, 108 (17), 6781-6786.

 

2010

37. Diastereoselective Synthesis of (±)-Heliotropamide by a One-Pot, Four-Component Reaction. Ashkaan Younai, Gregory F. Chin, and Jared T. Shaw. J. Org. Chem., 2010, 75 (23), pp 8333–8336.

36. Practical Synthesis of PC190723, an Inhibitor of the Bacterial Cell Division Protein FtsZ. Nohemy A. Sorto, Marilyn M. Olmstead, and Jared T. Shaw. J. Org. Chem., 2010, 75 (22), pp 7946–7949.

35. High-Throughput Methods of Chemical Synthesis Applied to the Preparation of Inhibitors of Protein-Protein Interactions. Annaliese K. Franz, Jared T. Shaw, Yuchen Tang. Protein Surface Recognition: Approaches for Drug Discovery (Wiley-Interscience; Eds. E. Giralt, M. Peczuh, X. Salvatella) 2010, pp 157-210.

34. Synthesis of Antimicrobial Natural Products Targeting FtsZ: (+)-Totarol and Related Totarane Diterpenes. Michelle B. Kim and Jared T. Shaw. Org. Lett., 2010, 12 (15), pp 3324–3327.

33. Organic Linking (Editors Letter). Jared T. Shaw and Matt McIntosh. ACS Chem. Biol., 2010, 5 (3), pp 255–256.

32. Recent advances in multicomponent reactions for diversity-oriented synthesis. James E. Biggs-Houck Ashkaan Younai, and Jared T. Shaw. Curr. Opin. Chem. Biol., 2010, 14 (3), pp 371-382.

 

2009

31. One-Step Synthesis of Complex Nitrogen Heterocycles from Imines and Alkyl-Substituted Maleic Anhydrides. Yuchen Tang, James C. Fettinger and Jared T. Shaw. Org. Lett., 2009, 11 (17), pp 3802-3805.

30. Naturally diverse: highlights in versatile synthetic methods enabling target- and diversity-oriented synthesis. Jared T. Shaw. Nat. Prod. Rep., 2009, 26 (1), pp 11-26.

29. Cyclic Anhydrides in Formal Cycloadditions and Multicomponent Reactions. Marcos González-López, and Jared T. Shaw. Chem. Rev., 2009, 109 (1), pp 164–189.

 

2008

28. Zinc-Catalyzed Silylation of Terminal Alkynes. Ronald J. Rahaim, Jr. and Jared T. Shaw. J. Org. Chem., 2008, 73 (7), pp 2912-2915.

27. Chemical Inhibition of the Mitochondrial Division Dynamin Reveals Its Role in Bax/Bak-Dependent Mitochondrial Outer Membrane Permeabilization. Ann Cassidy-Stone, Jerry E. Chipuk, Elena Ingerman, Cheng Song, Choong Yoo, Tomomi Kuwana, Mark J. Kurth, Jared T. Shaw, Jenny E. Hinshaw, Douglas R. Green, Jodi Nunnari. Dev. Cell, 2008, 14 (2), pp 193-204.

26. Identification of the Molecular Target of Small Molecule Inhibitors of HDL Receptor SR-BI Activity. Thomas J. F. Nieland, Jared T. Shaw, Firoz A. Jaipuri, Jay L. Duffner, Angela N. Koehler, Sotirios Banakos, Vassilis I. Zannis, Tomas Kirchhausen, Monty Krieger. Biochemistry, 2008, 47 (1), pp 460–472.

 

2007

25. N-Benzyl-3-sulfonamidopyrrolidines as novel inhibitors of cell division in E. coli. Shubhasish Mukherjeea, Carolyn A. Robinsonb, Andrew G. Howea, Tali Mazora, Peter A. Wooda, Sameer Urgaonkara, Alan M. Hebertc, Debabrata RayChaudhurid, Jared T. Shaw. Bioorg. Med. Chem. Lett., 2007, 17 (23), pp 6651-6655.

24. Influence of HDL-cholesterol-elevating drugs on the in vitro activity of the HDL receptor SR-BI. Thomas J. F. Nieland, Jared T. Shaw, Firoz A. Jaipuri, Zoltan Maliga, Jay L. Duffner, Angela N. Koehler, and Monty Krieger. J. Lipid Res., 2007, 48 (8), pp 1832-1845.

23. Diastereoselective Synthesis of gamma-Lactams by a One-Pot, Four-Component Reaction. Jingqiang Wei and Jared T. Shaw. Org. Lett., 2007, 9 (20), pp 4077–4080.

22. Synthesis of Kaempferitrin. Sameer Urgaonkar and Jared T. Shaw. J. Org. Chem., 2007, 72 (12), pp 4582–4585.

21. Synthesis and Stereochemical Assignment of Brasilibactin A. Judith M. Mitchell and Jared T. Shaw. Org. Lett., 2007, 9 (9), pp 1679–1681.

20. Synthesis of Diverse Lactam Carboxamides Leading to the Discovery of a New Transcription-Factor Inhibitor. Pui Yee Ng, Yuchen Tang, Wendy M. Knosp, H. Scott Stadler, Jared T. Shaw. Angew. Chem. Int. Ed., 2007, 46 (28), pp 5352–5355.

 

2006

19. Cycloaddition Reactions of Imines with 3-Thiosuccinic Anhydrides: Synthesis of the Tricyclic Core of Martinellic Acid. Pui Yee Ng, Craig E. Masse, Jared T. Shaw. Org. Lett., 2006, 8 (18), pp 3999–4002.

18. Divergent Structural Complexity from a Linear Reaction Sequence: Synthesis of Fused and Spirobicyclic γ-Lactams from Common Synthetic Precursors. Craig E. Masse, Pui Yee Ng, Yoshiyuki Fukase, María Sánchez-Roselló, and Jared T. Shaw. J. Comb. Chem., 2006, 8 (3), pp 293–296.

17. A Structurally Diverse Library of Polycyclic Lactams Resulting from Systematic Placement of Proximal Functional Groups. Judith M. Mitchell and Jared T. Shaw. Angew. Chem. Int. Ed., 2006, 45 (11), pp 1722 –1726.

 

2005

16. Synthesis of Antimicrobial Natural Products Targeting FtsZ: (±)-Dichamanetin and (±)-2'''-Hydroxy-5''-benzylisouvarinol-B. Sameer Urgaonkar, Henry S. La Pierre, Israel Meir, Henrik Lund, Debabrata RayChaudhuri, Jared T. Shaw. Org. Lett., 2005, 7 (25), pp 5609–5612.

15. Stereoselective C-Glycosylation Reactions of Ribose Derivatives: Electronic Effects of Five-Membered Ring Oxocarbenium Ions. Catharine H. Larsen, Brian H. Ridgway, Jared T. Shaw, Deborah M. Smith, K. A. Woerpel. J. Am. Chem. Soc., 2005, 127 (31), pp 10879–10884.

 

Postdoc (Harvard, 1999-2002; Prof. David A. Evans)

14. A New Copper Acetate-Bis(oxazoline)-Catalyzed, Enantioselective Henry Reaction. David A. Evans, Daniel Seidel, Magnus Rueping, Hon Wai Lam, Jared T. Shaw, C. Wade Downey. J. Am. Chem. Soc., 2003, 125 (42), pp 12692–12693.

13. Recent advances in asymmetric synthesis with chiral imide auxiliaries. David A. Evans and Jared T. Shaw. L'Actualité Chimique 2003, pp 35-38.

12. Magnesium Halide-Catalyzed Anti-Aldol Reactions of Chiral N-Acylthiazolidinethiones. David A. Evans, C. Wade Downey, Jared T. Shaw, Jason S. Tedrow. Org. Lett., 2002, 4 (7), pp 1127–1130.

11. Diastereoselective Magnesium Halide-Catalyzed anti-Aldol Reactions of Chiral N-Acyloxazolidinones. David A. Evans, Jason S. Tedrow, Jared T. Shaw, C. Wade Downey. J. Am. Chem. Soc., 2002, 124 (3), pp 392–393.

 

PhD (UC Irvine, 1994-1999; Prof. Keith Woerpel)

10. Diastereoselective Nucleophilic Substitution Reactions of Oxasilacyclopentane Acetals: Application of the Inside Attack Model for Reactions of Five-Membered Ring Oxocarbenium Ions. Teresa J. Bear, Jared T. Shaw, K. A. Woerpel. J. Org. Chem., 2002, 67 (7), pp 2056–2064.

09. A Stereoelectronic Model To Explain the Highly Stereoselective Reactions of Nucleophiles with Five-Membered-Ring Oxocarbenium Ions. Catharine H. Larsen, Brian H. Ridgway, Jared T. Shaw, K. A. Woerpel. J. Am. Chem. Soc., 1999, 121 (51), pp 12208–12209.

08. Divergent Diastereoselectivity in the Addition of Nucleophiles to tetrahydrofuran-derived Oxonium Ions. Jared T. Shaw, K. A. Woerpel. Tetrahedron, 1999, 55 (29), pp 8747-8756.

06. Preparation and Synthetic Utility of Oxasilacyclopentane Acetals Derived from Siliranes. Jared T. Shaw, K. A. Woerpel. Tetrahedron, 1997, 53 (48), pp 16597-16606.

05. Divergent Diastereoselectivity in the Addition of Nucleophiles to Five-Membered-Ring Oxonium Ions. Jared T. Shaw, K.A. Woerpel. J. Org. Chem., 1997, 62 (20), pp 6706–6707.

04. Tandem Aldol-Tishchenko Reactions of Lithium Enolates: A Highly Stereoselective Method for Diol and Triol Synthesis. Paul M. Bodnar, Jared T. Shaw, K.A. Woerpel. J. Org. Chem., 1997, 62 (17), pp 5674–5675.

03. Stereo- and Regioselectivity of Reactions of Siliranes with Aldehydes and Related Substrates. Paul M. Bodnar, Wylie S. Palmer, Brian H. Ridgeway, Jared T. Shaw, Jacqueline H. Smitrovich, K.A. Woerpel. J. Org. Chem., 1997, 62 (14), pp 4737–4745.

02. Stereoselective Insertion of Formamides into the C-Si Bond of Siliranes. Jared T. Shaw, K.A. Woerpel. J. Org. Chem., 1997, 62 (3), pp 442–443.

01. Stereo- and Regiochemistry of Aldehyde insertions into the C-Si Bonds of Siliranes. Paul M. Bodnar, Wylie S. Palmer, Jared T. Shaw, Jacqueline H. Smitrovich, Jennifer D. Sonnenberg, Alice L. Presley, K.A. Woerpel. J. Am. Chem. Soc., 1995, 117 (42), pp 10575–10576.

Gilead Sciences (1993-1994)

07. Synthesis and Hybridization property of an Oligonucleotide Containing a 3'-thioformacetal Linked Pentathymidylate. Jiancun Zhang, Jared T. Shaw, Mark D. Matteucci. Bioorg. Med. Chem. Lett., 1999, 9 (3), pp 319-322.