Publications

Publications

 

2017

73. Diastereoselective Base-Catalyzed Formal [4+2] Cycloadditions of N-Sulfonyl Imines and Cyclic Anhydrides. Stephen W. Laws, Lucas C. Moore, Michael J. Di Maso, Q. Nhu N. Nguyen, Dean J. Tantillo, and Jared T. Shaw. Org Lett. 2017, 19, 2466–2469

72. Targeting quinolone- and aminocoumarin-resistant bacteria with new gyramide analogs that inhibit DNA gyrase. K. Hurley, T. Santos, M. Fensterwald, M. Rajendran, J. Moore, E. Balmond, B. Blahnik, K. Faulkner, M. Foss, V. Heinrich, M. Lammers, L. Moore, G. Reynolds, G. Shearn-Nance, B. Stearns, Z. Yao, J. T. Shaw and D. Weibel. Med. Chem. Commun., 2017, 8, 942-951

 

2016

71. Asymmetric Synthesis of Homocitric Acid Lactone. Leslie A. Nickerson, Valerie Huynh, Edward I. Balmond, Stephen P. Cramer, and Jared T. Shaw. J. Org. Chem. 2016, 81, 11404-11408.

70. Comparative Evaluation of Substituent Effect on the Photochromic Properties of Spiropyrans and Spirooxazines. Edward I. Balmond, Brandon K. Tautges, Andrea L. Faulkner, Victor W. Or, Blanka M. Hodur, Jared T. Shaw, and Angelique Y. Louie. J. Org. Chem. 2016, 81, 8744–8758.

69. Plastidial Metabolite MEcPP Induces a Transcriptionally Centered Stress-Response Hub via the Transcription Factor CAMTA3. Geoffrey Benn, Marta Bjornson, Haiyan Ke, Amancio De Souza, Edward I. Balmond, Jared T. Shaw, and Katayoon Dehesha. PNAS 2016, 113, 8855-8860.

68. Synthesis of Esters by in Situ Formation and Trapping of Diazoalkanes. Richard A. Squitieri, Galen P. Shearn-Nance, Jason E. Hein, and Jared T. Shaw. J. Org. Chem., 2016, 81, 5278–5284.

67. Synthesis of (±)-Bisavenanthramide B-6 by an Anionic Anhydride Mannich Reaction. Michael J. Di Maso, Gabriella M. Nepomuceno, Michael A. St. Peter, Haley H. Gitre, Kevin S. Martin, and Jared T. Shaw. Org. Lett. 2016, 18, 1740-1743.

66. Diastereoselective Synthesis of and Mechanistic Understanding for the Formation of 2-Piperidinones from Imines and Cyano-Substituted Anhydrides. Michael J. Di Maso, Kevin M. Snyder, Fábio De Souza Fernandes, Ommidala Pattawong, Darlene Q. Tan, James C. Fettinger, Paul Ha-Yeon Cheong, Jared T. Shaw. Chem. Eur. J. 2016, 22, 4794-4801.

65. Toward Structural Correctness: Aquatolide and the Importance of 1D Proton NMR FID Archiving. Guido F. Pauli, Matthias Niemitz, Jonathan Bisson, Michael W. Lodewyk, Cristian Soldi, Jared T. Shaw, Dean J. Tantillo, Jordy M. Saya, Klaas Vos, Roel A. Kleinnijenhuis, Henk Hiemstra, Shao-Nong Chen, James B. McAlpine, David C. Lankin, and J. Brent Friesen. J. Org. Chem. 2016, 81, 878-889.

64. Targeting the Bacterial Division Protein FtsZ. Katherine A. Hurley, Thiago M. A. Santos, Gabriella M. Nepomuceno, Valerie Huynh, Jared T. Shaw, and Douglas B. Weibel. J. Med. Chem., 2016, 59, 6975–6998.

2015

63. 4-Methyl-1-(2-(phenylsulfonyl)ethyl)-2,6,7-trioxabicyclo[2.2.2]octane. Michael J. Di Maso, Michael A. St. Peter, Jared T. Shaw . Org. Synth. 2015, 92, 328-341.

62. Preparation of a conjugation-ready thiol responsive molecular switch. Brandon Tautges, Victor Or, Joel Garcia, Jared T. Shaw, and Angelique Y. Louie. Tetrahedron Lett., 2015, 56, 6569-6573.

61. Synthesis of the diaryl ether cores common to chrysophaentins A, E and F. Anthony J. Brockway, Charles I. Grove, Maximillian E. Mahoney, and Jared T. Shaw. Tetrahedron Lett., 2015, 2015, 56, 3396-3401.

60. Synthesis and Evaluation of Quinazolines as Inhibitors of the Bacterial Cell Division Protein FtsZ. Gabriella M. Nepomuceno, Katie M. Chan, Valerie Huynh, Kevin S. Martin, Jared T. Moore, Terrence E. O’Brien, Luiz A. E. Pollo, Francisco J. Sarabia, Clarissa Tadeus, Zi Yao, David E. Anderson, James B. Ames, and Jared T. Shaw. ACS. Med. Chem. Lett, 2015, 6(3), pp 308-312.

2014

59. Enantioselective Intramolecular C–H Insertion Reactions of Donor–Donor Metal Carbenoids. Cristian Soldi , Kellan N. Lamb , Richard A. Squitieri , Marcos González-López , Michael J. Di Maso , and Jared T. Shaw. J. Am. Chem. Soc., 2014, 136 (43), pp 15142–15145.

58. Chapter 10 – Studies in the Synthesis of Biaryl Natural Products: The 6,6′-Binaphthopyranones. Michael J. Di Maso, Charles I. Grove, Jared T. Shaw. Strategies and Tactics in Organic Synthesis, 2014, 10, pp 225-248.

57. Diastereoselective Synthesis of gamma- and delta-Lactams From Imines and Sulfone-Substituted Anhydrides. Nohemy A. Sorto , Michael J. Di Maso , Manuel A. Muñoz , Ryan J. Dougherty , James C. Fettinger , and Jared T. Shaw. J. Org. Chem., 2014, 79 (6), pp 2601–2610.

2013

56. Enantioselective Synthesis of Isotopically Labeled Homocitric Acid Lactone. Jared T. Moore, Nadine V. Hanhan, Maximillian E. Mahoney, Stephen P. Cramer, and Jared T. Shaw. Org. Lett., 2013, 15 (22), pp 5615–5617.

55. Stereocontrol in Asymmetric γ-Lactam Syntheses from Imines and Cyanosuccinic Anhydrides. Ommidala Pattawong, Darlene Q. Tan, James C. Fettinger, Jared T. Shaw, and Paul Ha-Yeon Cheong. Org. Lett., Article, 15 (19), pp 5130–5133.

54. Stereoselective Synthesis of γ-Lactams from Imines and Cyanosuccinic Anhydrides. Darlene Q. Tan, Ashkaan Younai, Ommidala Pattawong, James C. Fettinger, Paul Ha-Yeon Cheong, and Jared T. Shaw. Org. Lett., Article, 15 (19), pp 5126–5129.

53. Synthesis of a Library of “Lead-like” γ-Lactams by a One Pot, Four-Component Reaction. Kevin S. Martin, Michael J. Di Maso, James C. Fettinger, and Jared T. Shaw. ACS Comb. Sci., 2013, 15 (7), pp 356–362.

52. Design and Synthesis of Mimics of the T7-loop of FtsZ. Nohemy A. Sorto, Phillip P. Painter, James C. Fettinger, Dean J. Tantillo, and Jared T. Shaw. Org. Lett., 2013, 15 (11), pp 2700–2703.

51. Mechanism of Alkoxy Groups Substitution by Grignard Reagents on Aromatic Rings and Experimental Verification of Theoretical Predictions of Anomalous Reactions. Gonzalo Jimenez-Oses, Anthony J. Brockway, Jared T. Shaw, and K.N. Houk. J. Am. Chem. Soc., 2013, 135 (17), pp 6633–6642.

2012

50. The Correct Structure of Aquatolide—Experimental Validation of a Theoretically-Predicted Structural Revision. Michael W. Lodewyk, Cristian Soldi, Paul B. Jones, Marilyn M. Olmstead, Juan Rita, Jared T. Shaw, and Dean J. Tantillo. J. Am. Chem. Soc., 2012, 134 (45), pp 18550–18553.

49. Catalytic alkene cyclization reactions for the stereoselective synthesis of complex “terpenoid-like” heterocycles. Jared T. Moore, Cristian Soldi, James C. Fettinger and Jared T. Shaw. Chem. Sci., 2013,4, 292-296.

48. Comparison of Small Molecule Inhibitors of the Bacterial Cell Division Protein FtsZ and Identification of a Reliable Cross-Species Inhibitor. David E. Anderson, Michelle B. Kim, Jared T. Moore, Terrence E. O’Brien, Nohemy A. Sorto, Charles I. Grove, Laura L. Lackner, James B. Ames, and Jared T. Shaw. ACS Chem. Biol., 2012, 7 (11), pp 1918–1928.

47. The Synthesis and Antimicrobial Activity of Heterocyclic Derivatives of Totarol. Michelle B. Kim, Terrence E. O’Brien, Jared T. Moore, David E. Anderson, Marie H. Foss, Douglas B. Weibel, James B. Ames, and Jared T. Shaw. ACS Med. Chem. Lett., 2012, 3, 818−822.

46. Synthesis of 6,6′-Binaphthopyran-2-one Natural Products: Pigmentosin A, Talaroderxines A and B. Charles I. Grove, Michael J. Di Maso, Firoz A. Jaipuri, Michelle B. Kim, and Jared T. Shaw. Org. Lett., 2012, 14 (17), pp 4338–4341.

45. Influence of Chiral Thiols on the Diastereoselective Synthesis of γ-Lactams from Cyclic Anhydrides. Ashkaan Younai, James C. Fettinger, and Jared T. Shaw. Tetrahedron, 2012, 68 (22), pp 4320-4327.

44. Second-Generation Synthesis of (-)-Viriditoxin. Charles I. Grove, James C. Fettinger, and Jared T. Shaw. Synthesis, 2012, 44 (3), pp 362-371.

43. Synthesis of a γ-Lactam Library via Formal Cycloaddition of Imines and Substituted Succinic Anhydrides. Darlene Q. Tan, Amy L. Atherton, Austin J. Smith, Cristian Soldi, Katherine A. Hurley, James C. Fettinger, and Jared T. Shaw. ACS Comb. Sci., 2012, 14 (3), pp 218–223.

42. Carbon–Carbon Bond-Forming Reactions of α-Thioaryl Carbonyl Compounds for the Synthesis of Complex Heterocyclic Molecules. James E. Biggs-Houck, Rebecca L. Davis, Jingqiang Wei, Brandon Q. Mercado, Marilyn M. Olmstead, Dean J. Tantillo, and Jared T. Shaw. J. Org. Chem., 2012, 77 (1), pp 160–172.

2011

41. Direct Displacement of Alkoxy Groups of Vinylogous Esters by Grignard Reagents. Anthony Brockway, Marcos Gonzalez-Lopez, James C. Fettinger, and Jared T. Shaw. J. Org. Chem., 2011, 76 (9), pp 3515–3518.

40. Synthesis of (-)-Viriditoxin: A 6,6’-Binaphthopyran-2-one that Targets the Bacterial Cell Division Protein FtsZ. Young Sam Park, Charles I. Grove, Marcos Gonzalez-Lopez, Sameer Urgaonkar, James C. Fettinger, and Jared T. Shaw. Angew. Chem. Int. Ed., 2011, 50 (16), pp 3730–3733.

39. N-Benzyl-3-sulfonamidopyrrolidines Are a New Class of Bacterial DNA Gyrase Inhibitors. Marie H. Foss, Katherine A. Hurley, Nohemy A. Sorto, Laura L. Lackner, Kelsey M. Thornton, Jared T. Shaw, and Douglas B. Weibel. ACS Med. Chem. Lett., 2011, 2 (4), pp 289–292.

38. Ammonia synthons for the multicomponent assembly of complex γ-lactams. Darlene Q. Tan, Kevin S. Martin, James C. Fettinger, and Jared T. Shaw. PNAS, 2011, 108 (17), 6781-6786.

2010

37. Diastereoselective Synthesis of (±)-Heliotropamide by a One-Pot, Four-Component Reaction. Ashkaan Younai, Gregory F. Chin, and Jared T. Shaw. J. Org. Chem., 2010, 75 (23), pp 8333–8336.

36. Practical Synthesis of PC190723, an Inhibitor of the Bacterial Cell Division Protein FtsZ. Nohemy A. Sorto, Marilyn M. Olmstead, and Jared T. Shaw. J. Org. Chem., 2010, 75 (22), pp 7946–7949.

35. “High-Throughput Methods of Chemical Synthesis Applied to the Preparation of Inhibitors of Protein-Protein Interactions.” Annaliese K. Franz, Jared T. Shaw, Yuchen Tang. Protein Surface Recognition: Approaches for Drug Discovery (Wiley-Interscience; Eds. E. Giralt, M. Peczuh, X. Salvatella) 2010, pp 157-210.

34. Synthesis of Antimicrobial Natural Products Targeting FtsZ: (+)-Totarol and Related Totarane Diterpenes. Michelle B. Kim and Jared T. Shaw. Org. Lett., 2010, 12 (15), pp 3324–3327.

33.“Organic Linking” (Editors Letter). Jared T. Shaw and Matt McIntosh. ACS Chem. Biol., 2010, 5 (3), pp 255–256.

32. Recent advances in multicomponent reactions for diversity-oriented synthesis. James E. Biggs-Houck Ashkaan Younai, and Jared T. Shaw. Curr. Opin. Chem. Biol., 2010, 14 (3), pp 371-382.

2009

31. One-Step Synthesis of Complex Nitrogen Heterocycles from Imines and Alkyl-Substituted Maleic Anhydrides. Yuchen Tang, James C. Fettinger and Jared T. Shaw. Org. Lett., 2009, 11 (17), pp 3802-3805.

30. Cyclic Anhydrides in Formal Cycloadditions and Multicomponent Reactions. Marcos González-López, and Jared T. Shaw. Chem. Rev., 2009, 109 (1), pp 164–189.

29. Naturally diverse: highlights in versatile synthetic methods enabling target- and diversity-oriented synthesis. Jared T. Shaw. Nat. Prod. Rep., 2009, 26 (1), pp 11-26.

2008

28. Zinc-Catalyzed Silylation of Terminal Alkynes. Ronald J. Rahaim, Jr. and Jared T. Shaw. J. Org. Chem., 2008, 73 (7), pp 2912-2915.

27. Chemical Inhibition of the Mitochondrial Division Dynamin Reveals Its Role in Bax/Bak-Dependent Mitochondrial Outer Membrane Permeabilization. Ann Cassidy-Stone, Jerry E. Chipuk, Elena Ingerman, Cheng Song, Choong Yoo, Tomomi Kuwana, Mark J. Kurth, Jared T. Shaw, Jenny E. Hinshaw, Douglas R. Green, Jodi Nunnari. Dev. Cell, 2008, 14 (2), pp 193-204.

26. Identification of the Molecular Target of Small Molecule Inhibitors of HDL Receptor SR-BI Activity. Thomas J. F. Nieland, Jared T. Shaw, Firoz A. Jaipuri, Jay L. Duffner, Angela N. Koehler, Sotirios Banakos, Vassilis I. Zannis, Tomas Kirchhausen, Monty Krieger. Biochemistry, 2008, 47 (1), pp 460–472.

2007

25. N-Benzyl-3-sulfonamidopyrrolidines as novel inhibitors of cell division in E. coli. Shubhasish Mukherjeea, Carolyn A. Robinsonb, Andrew G. Howea, Tali Mazora, Peter A. Wooda, Sameer Urgaonkara, Alan M. Hebertc, Debabrata RayChaudhurid, Jared T. Shaw. Bioorg. Med. Chem. Lett., 2007, 17 (23), pp 6651-6655.

24. Influence of HDL-cholesterol-elevating drugs on the in vitro activity of the HDL receptor SR-BI. Thomas J. F. Nieland, Jared T. Shaw, Firoz A. Jaipuri, Zoltan Maliga, Jay L. Duffner, Angela N. Koehler, and Monty Krieger. J. Lipid Res., 2007, 48 (8), pp 1832-1845.

23. Diastereoselective Synthesis of gamma-Lactams by a One-Pot, Four-Component Reaction. Jingqiang Wei and Jared T. Shaw. Org. Lett., 2007, 9 (20), pp 4077–4080.

22. Synthesis of Kaempferitrin. Sameer Urgaonkar and Jared T. Shaw. J. Org. Chem., 2007, 72 (12), pp 4582–4585.

21. Synthesis and Stereochemical Assignment of Brasilibactin A. Judith M. Mitchell and Jared T. Shaw. Org. Lett., 2007, 9 (9), pp 1679–1681.

20. Synthesis of Diverse Lactam Carboxamides Leading to the Discovery of a New Transcription-Factor Inhibitor. Pui Yee Ng, Yuchen Tang, Wendy M. Knosp, H. Scott Stadler, Jared T. Shaw. Angew. Chem. Int. Ed., 2007, 46 (28), pp 5352–5355.

2006

19. Cycloaddition Reactions of Imines with 3-Thiosuccinic Anhydrides: Synthesis of the Tricyclic Core of Martinellic Acid. Pui Yee Ng, Craig E. Masse, Jared T. Shaw. Org. Lett., 2006, 8 (18), pp 3999–4002.

18. Divergent Structural Complexity from a Linear Reaction Sequence: Synthesis of Fused and Spirobicyclic γ-Lactams from Common Synthetic Precursors. Craig E. Masse, Pui Yee Ng, Yoshiyuki Fukase, María Sánchez-Roselló, and Jared T. Shaw. J. Comb. Chem., 2006, 8 (3), pp 293–296.

17. A Structurally Diverse Library of Polycyclic Lactams Resulting from Systematic Placement of Proximal Functional Groups. Judith M. Mitchell and Jared T. Shaw. Angew. Chem. Int. Ed., 2006, 45 (11), pp 1722 –1726.

2005

16. Synthesis of Antimicrobial Natural Products Targeting FtsZ: (±)-Dichamanetin and (±)-2”’-Hydroxy-5”-benzylisouvarinol-B. Sameer Urgaonkar, Henry S. La Pierre, Israel Meir, Henrik Lund, Debabrata RayChaudhuri, Jared T. Shaw. Org. Lett., 2005, 7 (25), pp 5609–5612.

15. Stereoselective C-Glycosylation Reactions of Ribose Derivatives: Electronic Effects of Five-Membered Ring Oxocarbenium Ions. Catharine H. Larsen, Brian H. Ridgway, Jared T. Shaw, Deborah M. Smith, K. A. Woerpel. J. Am. Chem. Soc., 2005, 127 (31), pp 10879–10884.

2002-2003

14. A New Copper Acetate-Bis(oxazoline)-Catalyzed, Enantioselective Henry Reaction. David A. Evans, Daniel Seidel, Magnus Rueping, Hon Wai Lam, Jared T. Shaw, C. Wade Downey. J. Am. Chem. Soc., 2003, 125 (42), pp 12692–12693.

13. Recent advances in asymmetric synthesis with chiral imide auxiliaries. David A. Evans and Jared T. Shaw. L’Actualité Chimique 2003, pp 35-38.

12. Magnesium Halide-Catalyzed Anti-Aldol Reactions of Chiral N-Acylthiazolidinethiones. David A. Evans, C. Wade Downey, Jared T. Shaw, Jason S. Tedrow. Org. Lett., 2002, 4 (7), pp 1127–1130.

11. Diastereoselective Magnesium Halide-Catalyzed anti-Aldol Reactions of Chiral N-Acyloxazolidinones. David A. Evans, Jason S. Tedrow, Jared T. Shaw, C. Wade Downey. J. Am. Chem. Soc., 2002, 124 (3), pp 392–393.

10. Diastereoselective Nucleophilic Substitution Reactions of Oxasilacyclopentane Acetals: Application of the Inside Attack Model for Reactions of Five-Membered Ring Oxocarbenium Ions. Teresa J. Bear, Jared T. Shaw, K. A. Woerpel. J. Org. Chem., 2002, 67 (7), pp 2056–2064.

1995-1999

09. A Stereoelectronic Model To Explain the Highly Stereoselective Reactions of Nucleophiles with Five-Membered-Ring Oxocarbenium Ions. Catharine H. Larsen, Brian H. Ridgway, Jared T. Shaw, K. A. Woerpel. J. Am. Chem. Soc., 1999, 121 (51), pp 12208–12209.

08. Divergent Diastereoselectivity in the Addition of Nucleophiles to tetrahydrofuran-derived Oxonium Ions. Jared T. Shaw, K. A. Woerpel. Tetrahedron, 1999, 55 (29), pp 8747-8756.

07. Synthesis and Hybridization property of an Oligonucleotide Containing a 3′-thioformacetal Linked Pentathymidylate. Jiancun Zhang, Jared T. Shaw, Mark D. Matteucci. Bioorg. Med. Chem. Lett., 1999, 9 (3), pp 319-322.

06. Preparation and Synthetic Utility of Oxasilacyclopentane Acetals Derived from Siliranes. Jared T. Shaw, K. A. Woerpel. Tetrahedron, 1997, 53 (48), pp 16597-16606.

05. Divergent Diastereoselectivity in the Addition of Nucleophiles to Five-Membered-Ring Oxonium Ions. Jared T. Shaw, K.A. Woerpel. J. Org. Chem., 1997, 62 (20), pp 6706–6707.

04. Tandem Aldol-Tishchenko Reactions of Lithium Enolates: A Highly Stereoselective Method for Diol and Triol Synthesis. Paul M. Bodnar, Jared T. Shaw, K.A. Woerpel. J. Org. Chem., 1997, 62 (17), pp 5674–5675.

03. Stereo- and Regioselectivity of Reactions of Siliranes with Aldehydes and Related Substrates. Paul M. Bodnar, Wylie S. Palmer, Brian H. Ridgeway, Jared T. Shaw, Jacqueline H. Smitrovich, K.A. Woerpel. J. Org. Chem., 1997, 62 (14), pp 4737–4745.

02. Stereoselective Insertion of Formamides into the C-Si Bond of Siliranes. Jared T. Shaw, K.A. Woerpel. J. Org. Chem., 1997, 62 (3), pp 442–443.

01. Stereo- and Regiochemistry of Aldehyde insertions into the C-Si Bonds of Siliranes. Paul M. Bodnar, Wylie S. Palmer, Jared T. Shaw, Jacqueline H. Smitrovich, Jennifer D. Sonnenberg, Alice L. Presley, K.A. Woerpel. J. Am. Chem. Soc., 1995, 117 (42), pp 10575–10576.